Dr. Phuah Chum Mok
CHIEF SCIENTIST | SINGAPORE
Dr. Puah Chum Mok
Dr Puah obtained his PhD (Steroid Biochemistry) from London University UK His working experience includes, (a) toxin extractions at the Medical Research Council at Carshalton, Surrey, UK (b) extractions and measurements of hormones in biological samples at the Institute of Urology (c) the Royal Postgraduate Medical School, Hammersmith Hospital on prostatic tumors (d) Clinical Research Lab at Harley Street, London in infertility and test tube baby program (e) Production manager at Diagnostic Biotechnology P/L at Singapore Science Park (production of HIV, HTLV 1, EBV and dengue virus, medical diagnostic test kits) (f) Lecturer & course manager in Diploma in Biotechnology, Singapore Polytechnic and design drug leads targeting dengue, West Nile virus and SARs viruses and (g) Biomax Technology Pte Ltd on waste management projects.
Dr Phua has published more than 40 scientific articles, some of which include
1) Infusions of hFSH and hLH in normal men. II serum testosterone response to infused hLH and hFSH. Acta Endocr. Vol.81 p234 (1976)
2) Measurements of unconjugated testosterone, 5 α-dihydrotestosterone and estradiol in human urine. Clin. Chim. Acta vol.80 p71 (1977)
3) A radioimmunochromatographic scanning method for the analysis of testosterone conjugates in urine and serum. J Chromatography vol.145 p.247 (1978)
4) Unconjugated dihydrotestosterone and testosterone levels in serum of patients with carcinoma of the prostate.Br. J. Cancer vol.38 p.195 (1978)
5) Changes in dihydrotestosterone and testosterone following endocrine manipulation in carcinoma of the prostate. Cancer Treatment Reports vol.63 p1192 (1979)
6) Androgen receptors in benign hypertrophied and malignant prostate. In: Steroid receptors and hormone-dependent neoplasia. Ed. JL Wittliff and O Dapunt, Masson Publishing, USA Inc, New York Chapter 18, p.149 (1980)
7) Changes of androgens with age in normal men. Age and Ageing vol.10 p.204 (1981)
8) Development of a Western Blot kit for the detection of human immunodeficiency virus, Type 1 (HV-1) IgM. In: Proc First Asia-Pacific Congress of Medical Virology 6-11 Nov, Singapore (1988).
9) Large-scale production and purification of human B-Lymphotropic virus (HBLV).In: Proc First Asia-Pacific Congress of Medical Virology 6-11 Nov, Singapore (1988).
10) Development of a screening and confirmatory procedure for human immunodeficiency virus, Type 2 (HIV-2). In: Proc First Asia-Pacific Congress of Medical Virology 6-11 Nov, Singapore (1988).
11) Large-scale processing of HIV-1 infected human T-Lymphocytes with new tangential flow filtration system. In: Proc First Asia-Pacific Congress of Medical Virology 6-11 Nov, Singapore (1988).
12) Maximum containment facility for the production of biohazardous materials. J. Institution Engineers Singapore vol.32 p73 (1992)
13) Development of a stater culture for palm oil wastewater treatment. In: Proc of Third Singapore Society for Microbiology – International Congress for Microbiology Abs.P39 (1993)
14) Studies of bleached and polymer-impregnated jadeite using scanning electron microscope. Aust J Gem vol.18 p.257 (1993)
15) Sensory evaluation of hydroponic vegetables grown in the tropics. In: International Conference on Agrotechnology in the Commonwealth 24-26 May 1995 Singapore
16) Comparative studies on the various hydroponic systems for growing vegetables in the tropics. In: International Conference on Agrotechnology in the Commonwealth 24-26 May 1995 Singapore
17) Bioremediation of wastewater containing phenolic compounds using locally derived starter culture. In: 3Rd Asia-Pacific Biochemical Engineering Conference June 13-15, 1996, Singapore.
18) A density functional theory (DFT) calculation of the geometry and vibrational spectrum of natural product, ginkgolide B.J Mol Struc (Theochem) vol. 528 p. 193 (2000)
19) Focused combinatorial library design based on structural diversity, druglikness and binding affinity score. J. Comb. Chem vol.7 p. 398 (2005)
20) Precious opal from Java. Gemological properties, micro- and nanostructures. In: 30Th International Gemological Conference 15-19 July 2007, Moscow, Russia
21) Efficient preparation of an acyclic permutant of kalata B1 from a recombinant fusion protein with thioredoxin. J Biotechnology vol.130 p.378 (2007)
22) Bioremediation of phenol-contaminated industrial wastewater using bacterial consortium-from laboratory to field. Water Air Soil Pollut vol.288 p.89 (2017)
23) Team member on drafting SS 633:2017: Code of Practice for Food Waste Management for Food processing/manufacturing establishments.
Additionally, he holds Patents with other inventors as follows:
a) Bioreactor for growing cells or tissue cultures (2005/SG)
b) Benzopyranone derivatives and their use as anti-viral agents (2005/China)
c) Bioremediation of hydrocarbon sludge (2007/SG)
d) Method for catalyzing a fusion polypeptide undergoing a cleavage reaction (2007/SG)
e) Hydrogen peroxide enhances enterokinase-catalyzed proteolytic cleavage of fusion protein (2008/SG)
f) Treatment of hydrocarbon-contaminated aqueous solution (2008/SG)
g) Treatment of organic waste (2011/ 23 countries)
h) Apparatus and system for treating organic mass (2018/ 8 countries)